Defining Alzheimer’s by biomarkers could improve clinical trials

Incorporating biomarkers into the research definition of Alzheimer’s disease should lead to delayed progression, better treatment and new criteria for clinical trials.
When we think about getting older, one of the things many people fear is developing dementia or Alz…Read More

Is the reversal of cellular aging possible through chemical means?

New research identifies six chemical cocktails that could reverse transcriptomic age.
Life is dependent on the preservation and storage of information. The genome and epigenome are the two central storehouses of information in eukaryotes, and although they work…Read More

Fatty acid C15:0 throws its hat into the longevity therapeutics ring

New study explores the longevity potential of C15:0 and how it rivals other leading longevity-enhancing compounds.
In the quest for unlocking the secrets of longevity and healthy aging, a recent paper has delved into the remarkable properties of a seemingly ordinary fatty…Read More

Hevolution pumps another $40 million into aging research projects

Aging research organizations, including the Buck and AFAR, benefit as Global Healthspan Summit funding commitments reach $100m.
The inaugural Global Healthspan Summit in Riyadh, Saudi Arabia closed its doors yesterday with yet another significant injection of funding into the…Read More

Buck Institute researchers identify how dietary restriction slows brain aging and increases lifespan

Discovered mechanism provides potential therapeutic targets to slow aging and age-related neurodegenerative diseases.
Caloric restriction is a well-documented way of improving both healthspan and lifespan; however, aspects of the the actual…Read More

Research shows gut inflammation associated with aging and Alzheimer’s

New study suggesting link between gut inflammation and brain changes adds to evidence for connection between the gut and Alzheimer’s disease.
A new study by researchers at the University of Wisconsin School of Medicine and Public Health has linked inflammation in the gut…Read More

New UK research cluster to study aging in model organisms

UKRI funds research iniative that will study age-related biological changes in mice and other animal models.
UK Research and Innovation (UKRI) has announced funding for a new aging-focused research cluster, with the aim of driving greater understanding of age-related diseases and…Read More

Gut health shines a light on Longevity

Using optogenetics on gut microbes can promote Longevity.
Our guts are full of trillions of bacteria, viruses, protozoa, archaea and fungi, both harmful and beneficial. Collectively they are referred to as the gut microbiome. As well as being vital for maintaining physical health, the gut microbiome plays…Read More